Table 3.

CD56 and CD16 expression on blood CD56^+low CCR5/CXCR3⁻, CD56^+int CCR5/CXCR3⁺, and CD56^+high CCR5/CXCR3⁺ NK-cell subsets.

		A		B		C		P values
		CD56+low CCR5/CXCR3−		CD56+int CCR5/CXCR3+		CD56+high CCR5/CXCR3+		A versus B	B versus C	A versus C
CD56	% (+) cells	100.0 ± 0.0	(100.0-100.0)	100.0 ± 0.0	(100.0-100.0)	100.0 ± 0.0	(100.0-100.0)	—	—	—
	MFI	466 ± 108	(303–623)	615 ± 149	(416–999)	2926 ± 578	(2161–3993)	0.022	<0.001	<0.001
	CV	57 ± 7	(41–66)	72 ± 11	(53–93)	37 ± 5	(27–48)	0.001	<0.001	<0.001
CD16	% (+) cells	99.9 ± 0.1	(99.9–100.0)	64.6 ± 23.6	(26.8–96.2)	28.7 ± 9.9	(9.9–43.5)	<0.001	<0.001	<0.001
	MFI	226 ± 107	(55–372)	84 ± 55	(25–201)	47 ± 18	(21–47)	0.001	0.026	<0.001
	CV	45 ± 5	(38–55)	79 ± 21	(45–122)	81 ± 21	(44–118)	<0.001	n.s.	<0.001

Data were obtained using the gating and analysis strategies described in Figure 2, where representative dot plots of these three NK-cell subsets are presented.

Results are expressed as mean ± standard deviation (minimum–maximum) of the percentage of positive (+) cells within each CD56⁺ NK-cell population and of the mean fluorescence intensity (MFI) and coefficient of variation (CV) of CD16 and CD56 expression.

n.s.: not statistically significant.