Table 2. Univariate analysis of clinicopathological prognostic factors and 5-year recurrence-free survival.
Characteristic | 5-Year RFS | 95% CI | p-value |
---|---|---|---|
Age (yr) | 0.387 | ||
<35 | 81.5 | 62.8-91.4 | |
35-60 | 87.9 | 83.4-91.3 | |
>60 | 92.9 | 74.4-98.2 | |
Tumor size (cm) | 0.056 | ||
≤2 | 89.4 | 84.5-92.9 | |
>2 | 83.9 | 75.5-89.5 | |
Histopathology | 0.072 | ||
Squamous cell carcinoma | 88.1 | 82.6-91.9 | |
Adenocarcinoma | 90.4 | 83.2-94.6 | |
Adenosquamous carcinoma | 77.1 | 47.9-91.3 | |
Lymph vascular space invasion | 0.123 | ||
Yes | 81.9 | 70.6-89.2 | |
No | 89.4 | 85.0-92.6 | |
Deep stromal invasion | <0.001 | ||
Yes | 76.1 | 63.3-84.9 | |
No | 90.8 | 86.5-93.7 | |
Lymph node metastasis | <0.001 | ||
Yes | 68.8 | 40.5-85.6 | |
No | 88.5 | 84.4-91.6 | |
Parametrial involvement | <0.001 | ||
Yes | 63.5 | 37.0-81.3 | |
No | 89.1 | 85.0-92.1 | |
Resection margin involvement | 0.023 | ||
Yes | 69.1 | 39.8-86.3 | |
No | 88.6 | 84.5-91.7 | |
Adjuvant therapy | 0.041 | ||
No | 89.7 | 85.3-92.8 | |
Radiation | 78.3 | 64.0-87.4 | |
Chemotherapy | 100.0 | - | |
Concurrent chemoradiation | 60.1 | 8.1-90.2 | |
Surgical waiting time (wk) | 0.230 | ||
≤4 | 83.6 | 74.0-89.8 | |
>4 | 89.1 | 84.3-92.5 | |
Surgical waiting time (wk) | 0.551 | ||
≤8 | 86.8 | 81.5-90.6 | |
>8 | 89.6 | 82.1-94.1 |
CI, confidence interval; RFS, recurrence-free survival.