Table 5. Multivariate analysis of clinicopathological prognostic factors and overall survival according to the cut-off point of surgical waiting time (4 and 8 weeks).
| Characteristic | HR | 95% CI | p-value |
|---|---|---|---|
| 4 Weeks | |||
| Surgical waiting time (wk) | 0.312 | ||
| ≤4 | 1 | - | |
| >4 | 0.7 | 0.4-1.3 | |
| Deep stromal invasion | 0.015 | ||
| Yes | 1 | - | |
| No | 2.4 | 1.2-4.8 | |
| Lymph node metastasis | 0.009 | ||
| Yes | 1 | - | |
| No | 3.6 | 1.5-8.6 | |
| 8 Weeks | |||
| Surgical waiting time (wk)* | |||
| In first 5 years | 0.097 | ||
| ≤8 | 1 | - | |
| >8 | 0.4 | 0.1-1.3 | |
| After 5 years | 0.021 | ||
| ≤8 | 1 | - | |
| >8 | 3.4 | 1.3-9.2 | |
| Deep stromal invasion | 0.009 | ||
| Yes | 1 | - | |
| No | 2.6 | 1.3-5.0 | |
| Lymph node metastasis | 0.009 | ||
| Yes | 1 | - | |
| No | 3.6 | 1.5-8.6 |
CI, confidence interval; HR, hazard ratio.
*Time-varying effect Cox model.