Table 2. Number and site of relapse according to adjuvant treatment and stage of disease.
Variable | No. | Relapse | Site of relapse | p-value* | ||
---|---|---|---|---|---|---|
Pelvic | Distant | Pelvic and distant | ||||
Observation | 55 | 17 (30.9) | 7 (12.7) | 8 (14.6 ) | 2 (3.6) | 0.084 |
Stage I-II | 48 | 12 (25) | 5 (10.4) | 6 (12.5) | 1 (2) | |
Stage III | 7 | 5 (71.4) | 2 (28.6) | 2 (28.6) | 1 (14.3) | |
EBRT | 98 | 32 (32.7) | 12 (12.2) | 15 (15.3) | 4 (4.1) | 0.039 |
Stage I-II | 60 | 21 (35) | 9 (15) | 10 (16.7) | 1 (1.7) | |
Stage III | 38 | 11 (28.9) | 3 (7.9) | 5 (13.2) | 3 (7.9) | |
Chemotherapy | 59 | 22 (37.3) | 9 (15.3) | 10 (16.9) | 3 (5.1) | 0.02 |
Stage I-II | 13 | 3 (23.1) | 2 (15.4) | 1 (7.7) | 0 | |
Stage III | 46 | 19 (41.3) | 7 (15.2) | 9 (19.6) | 3 (6.5) | |
Sequential chemo-EBRT | 42 | 7 (16.7) | 2 (4.8) | 3 (7.1) | 1 (2.4) | - |
Stage I-II | 13 | 1 (7.7) | 0 | 1 (7.7) | 0 | |
Stage III | 29 | 6 (20.7) | 2 (6.9) | 1 (3.4) | 1 (3.4) |
Values are presented as number (%).
EBRT, external beam radiotherapy.
*Fisher exact test for the reduction of relapse compared with sequential chemo-EBRT.