Table 4. Univariate and multivariate analysis of prognostic factors for overall survival.
Clinicopathological factor | Univariate | Multivariate | |||||
---|---|---|---|---|---|---|---|
HR | 95% CI | p-value | HR | 95% CI | p-value | ||
FIGO stage | III vs. IV | 1.39 | 0.88-2.19 | 0.16 | 1.31 | 0.81-2.12 | 0.28 |
Histologic subtype | Serous vs. non-serous | 1.05 | 0.58-1.91 | 0.84 | 0.84 | 0.44-1.62 | 0.61 |
Neoadjuvant chemotherapy | |||||||
No. of cycles | ≤4 vs. 5≤ | 1.11 | 0.67-1.84 | 0.69 | 1.48 | 0.85-2.55 | 0.16 |
Regimen | Taxane based vs. non-taxane | 1.01 | 0.64-1.59 | 0.98 | 1.02 | 0.61-1.70 | 0.94 |
Interval debulking surgery | |||||||
Systematic lymphadenectomy | Done vs. not done | 0.89 | 0.55-1.45 | 0.65 | 1.1 | 0.64-1.88 | 0.74 |
Excision of other organ(s) | Done vs. not done | 0.75 | 0.52-1.08 | 0.12 | 0.86 | 0.56-1.32 | 0.49 |
Ascites cytology | Negative vs. positive | 1.29 | 0.88-1.87 | 0.19 | 1.21 | 0.82-1.77 | 0.33 |
Lymph node metastasis | No vs. yes | 0.89 | 0.67-1.2 | 0.44 | 0.99 | 0.70-1.41 | 0.97 |
Gross residual lesion | No vs. yes | 4.03 | 2.46-6.61 | <0.001 | 4.14 | 2.39-7.16 | <0.001 |
CI, confidence interval; FIGO, International Federation of Gynecology and Obstetrics; HR, hazard ratio.