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. 2015 Oct 26;5:15636. doi: 10.1038/srep15636

Figure 4. Biodistribution of 99mTc-HMPAO-ENVs.

Figure 4

Mice were sacrificed at 0.5, 1, 3, 5 hr after 99mTc-HMPAO ENVs injection and radioactivity was measured for quantitative analysis of biodistribution (n = 4 for groups sacrificed at 0.5, 1 and 5 hr; n = 3 for a group sacrificed at 3 hr). As shown in SPECT images, 99mTc-HMPAO-ENVs were highly accumulated in liver, spleen and kidneys. Note that no significant uptake in brain unlike 99mTc-HMPAO used as a brain perfusion tracer. %ID/g represents counts of radioactivity normalized by injected dose and weights of organ. Data are presented as mean ± S.D.