Figure 2. EMG Recordings.

EMG signals were recorded from the temporal muscle contralateral to the FUS application. The grey region denotes when either the control (a) or the full sonication (b) with the transducer was being applied. Red dashed vertical lines indicate detected muscle activation. The horizontal green bar indicates the maximum signal recorded during the control period (indicated by the green dot) and subsequently used as the threshold to detect abnormal or large signals that occurred during the application of the FUS technique. Only recordings from NHP Z are shown, but NHP A showed similar responses. There was no abnormal or large muscle activity triggered by the alert FUS procedure.