Table 1. BBB opening per location for each NHP.
Target | NHP Z (Alert) | NHP A (Alert) | NHP Z(Anesthetized) | NHP A(Anesthetized) |
---|---|---|---|---|
Caudate | 125.6 mm3(n = 1) | 534.2 ± 261.2 mm3(n = 3/4) | N/A | N/A |
Putamen | 567.8 ± 251.6 mm3(n = 3/3) | 417.3 ± 133.4 mm3(n = 4/4) | 381.9 ± 245.6 mm3(n = 4/4) | 453.9 ± 94.0 mm3(n = 9/12) |
Thalamus | 697.7 ± 181.8 mm3(n = 5/6) | 352.1 mm3(n = 1/1) | 382.5 mm3(n = 1) | 400.4 mm3(n = 1) |
Averages volumes and standard deviations here reflect only when BBB opening was successful. The n values signify successful BBB opening/Total FUS procedures at that location.