Supplementary Table 1.

Top Gene Ontology (GO) terms for transcripts altered after SOX15 depletion in CPA cells

Term RNAseq Down	P Value	Term RNAseq UP	P Value
GO:0000278 ∼ mitotic cell cycle	3.26E−20	GO:0000079 ∼ regulation of cyclin-dependent protein kinase activity	4.40E−06
GO:0051301 ∼ cell division	6.39E−20	GO:0016192 ∼ vesicle-mediated transport	6.89E−06
GO:0000280 ∼ nuclear division	1.39E−19	GO:0051726 ∼ regulation of cell cycle	8.53E−06
GO:0007067 ∼ mitosis	1.39E−19	GO:0009991 ∼ response to extracellular stimulus	3.09E−05
GO:0022403 ∼ cell cycle phase	1.48E−19	GO:0006091 ∼ generation of precursor metabolites and energy	5.73E−05
GO:0000087 ∼ M phase of mitotic cell cycle	1.52E−19	GO:0045767 ∼ regulation of antiapoptosis	7.05E−05
GO:0022402 ∼ cell cycle process	4.58E−19	GO:0031667 ∼ response to nutrient levels	1.71E−04
GO:0007049 ∼ cell cycle	2.49E−18	GO:0007584 ∼ response to nutrient	2.63E−04
GO:0000279 ∼ M phase	2.96E−18	GO:0008219 ∼ cell death	5.87E−04
GO:0048285 ∼ organelle fission	3.08E−18	GO:0010033 ∼ response to organic substance	6.29E−04
GO:0007059 ∼ chromosome segregation	1.93E−10	GO:0042981 ∼ regulation of apoptosis	6.32E−04
GO:0008104 ∼ protein localization	4.68E−10	GO:0055114 ∼ oxidation reduction	6.36E−04
GO:0045184 ∼ establishment of protein localization	5.39E−10	GO:0042127 ∼ regulation of cell proliferation	6.77E−04
GO:0008654 ∼ phospholipid biosynthetic process	6.48E−10	GO:0016265 ∼ death	6.77E−04
GO:0015031 ∼ protein transport	2.46E−09	GO:0043067 ∼ regulation of programmed cell death	7.56E−04