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DNA repair pathways and associated lesions.
| Repair pathway | Activated in response to |
|---|---|
| Nucleotide excision repair (NER) | Bulky- and helix-distorting adducts |
| Base excision repair (BER) | Non-helix-distorting base lesions and SSBs |
| Mismatch repair (MMR) | Incorrect insertion, deletion, and base misincorporation |
| Non-homologous end joining (NHEJ) | DNA DSBs |
| Homologous recombination (HR) | DNA DSBs |
