Table 2.

Shock tube TBI models.

Study	Sex/species/age	Model	Injuries	Interval	Anesthesia	Outcome measures
Long et al. (74)	Male S. Dawley rats 2–3 months	5.3-m metal tube	Single	Single	Isoflurane	Cardiovascular; motor; cognition; structural integrity; vascular damage; degeneration
Budde et al. (75)	Unknown S. Dawley rats Unknown	3.3-m metal tube	Single mild and severe	Single	Isoflurane	Advanced imaging; anxiety; cognition; gliosis and degeneration; apoptosis
Genovese et al. (50)	Male S. Dawley rats 2–3 months	5.3-m metal tube	Repeat (3)	24 h	Isoflurane	Fear conditioning
Wang et al. (52)	Male C57BL6 mice 2–3 months	5.3-m metal tube	Repeat (3)	1 or 30 min	Isoflurane	Mitochondrial function; DNA fragmentation; righting reflex; apoptosis
Lucke-Wold et al. (6, 42)	Male S. Dawley rats 2–3 months	0.3-m metal tube	Single	Single	Isoflurane	Vascular damage; structural integrity; gliosis and degeneration
Logsdon et al. (41)	Male S. Dawley rats 2–3 months	0.3-m metal tube	Single	Single	Isoflurane	Vascular damage; endoplasmic reticulum stress; cell death; apoptosis; anxiety