Table 3.

Predictors of risk of recurrent SSTI in univariate and multivariate Cox regression models

Factor	Univariate HR	p-value	Multivariate HR (Final model)	p-value
	(95 % CI)		(95 % CI)
HAART	0.67 (0.31–1.44)	0.30
Trimethoprim-sulfamethoxazole	0.73 (0.28–1.91)	0.52
Azithromycin	1.38 (0.48–3.98)	0.55
Age (cont)	0.99 (0.96–1.03)	0.71
STD (any)	1.06 (0.49–2.27)	0.88
Chlamydia	1.18 (0.16–8.77)	0.87
Gonorrhea	4.96 (0.65–37.7)	0.12
Syphilis	0.49 (0.07–3.59)	0.48
Human papilloma virus (clinical)	1.58 (0.60–4.17)	0.35
Human papilloma virus (Pap)	1.12 (0.43–2.92)	0.82
Trichomonas	0.45 (0.06–3.33)	0.44
Catheter	4.62 (1.08–19.7)	0.04	6.50 (1.47–28.7)	0.01
Medicaid	0.64 (0.30–1.37)	0.25
End stage renal disease	0.70 (0.16–2.93)	0.62
Cancer	0.51 (0.07–3.73)	0.51
Diabetes	1.03 (0.39–2.69)	0.96
Hepatitis B	1.27 (0.38–4.20)	0.69
Hepatitis C	0.91 (0.32–2.61)	0.86
Incarceration	0.22 (0.03–1.65)	0.14
Other chronic liver disease	2.89 (1.00–8.35)	0.05	3.43 (1.02-11.5)	0.05
Men who have sex with men	0.81 (0.36–1.81)	0.60
IVDU	2.41 (0.98–5.91)	0.06	2.80 (1.02-7.65)	0.05
Male	0.87 (0.42–1.79)	0.71
African-American race	0.34 (0.11–1.00)	0.05	0.12 (0.03-0.41)	<0.01
Chronic skin disease: Any	1.36 (0.66–2.79)	0.41
Psoriasis	0.46 (0.06–3.39)	0.45
Lymphedema	4.12 (1.24–14.1)	0.02
CD4
100+	Reference
<100	1.13 (0.39–3.24)	0.83
Viral load
<1000	Reference		Reference
1000+	1.58	0.22	2.21 (0.99–4.94)	0.05
Initial SSTI type
Abscess	Reference
Furuncle	0.26 (0.03–1.91)	0.19
Cellulitis	0.66 (0.28–1.55)	0.34
Incision and drainage performed on initial SSTI	1.69 (0.82–3.47)	0.15
Initial SSTI S. aureus	2.10 (0.93–4.72)	0.07
Initial SSTI MRSA	2.21 (0.90–5.40)	0.08