Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
cGAS is required for the generation of hyperreactive T cells in Trex1−/− mice. (A–C) Flow-cytometric analysis of intracellular IFN-γ in response to PMA plus ionomycin in splenic CD4+ T cells or CD8+ T cells from 12-wk-old mice of indicated genotypes. (D) Similar to C, except that CD8 T cells in PBMC were analyzed. (E and F) Flow-cytometric analysis of T-bet in splenic CD4 (E) and CD8 (F) T cells from 12-wk-old mice. Error bars represent SD. *P < 0.05; **P < 0.01; ***P < 0.001.
