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cGAS is responsible for higher percentages of activated and memory T cells in Trex1−/− mice. (A and B) Representative flow-cytometric analysis of CD62L and CD44 expression in splenic CD4+ (A) and CD8+ T cells (B) from 12-wk-old mice of indicated genotypes. (C–E) Flow-cytometric analysis of expression of CD69 (C) and Ly6c (D) in splenic CD8+ T cells and CD69 (E) in splenic CD4+ T cells. Error bars represent SD. **P < 0.01; ***P < 0.001.
