Fig. 3.

Time-series transcriptome analyses reveal that most Ras^V12 cell lines reach a similar state. (A) Venn diagram showing the number of up-regulated genes (in parenthesis) at late, compared with early, passages in the R1, R3, R4, and R7 cell lines. (B) Heat map showing the results of GO category enrichment performed on the genes up-regulated at late time points compared with early time points in each cell line. Scale is in negative log₂ P value. Yellow, highly significant; blue, not significant.