Table S2.

Effect of ⁹⁰Y-daclizumab therapy

Patient	Total mCi per cycle, doses of 90Y-daclizumab administered	Maximum toxicity greater than grade 3	Development of human antibodies to daclizumab	Response	Response duration, d	Progression-free survival, d	Overall survival, d
1	15 × 4	Anemia, myelodysplasia	No	CR	314	400	1,289
2	15 × 6	None	No	SD	NA	280	735
3	10, 15 × 3	None	No	CR	230	298	947+
4	15 × 2	Neutropenia	No	PD	NA	75	259
5	10, 15 × 2	Thrombocytopenia	No	PR	163	240	864+
6	15, 5, 15 × 4, 10	Neutropenia	Yes	CR	323	441	824+
7	10, 15 × 5	None	No	PR	392	459	850+
8	10, 15 × 3	Lymphocytopenia	No	PR	114	140	488+
9	10 × 2	Neutropenia	Yes	CR	28	152	801+
10	10, 15	Neutropenia	No	PD	NA	97	97+
11	10, 15 × 4	None	No	CR	117	347	347+
12	10, 15 × 2	Myelodysplasia	No	CR	222	476	546+
13	10, 15 × 3	Myelodysplasia	No	PR	176	201	546+
14	10	None	No	PD	NA	27	81
15	10	None	No	PD	NA	68	138+
16	10, 15 × 4	None	No	CR	217	328	446+
17	10, 15 × 4	Lymphocytopenia, pneumonia	No	CR	245	355	421+
18	10, 15 × 5	None	No	CR	182	348	441+
19	10, 15 × 2	Lymphocytopenia	No	SD	NA	161	377
20	10, 15 × 2, 10, 5	None	No	CR	134	243	381+
21	10, 15	Thrombocytopenia	No	SD	NA	111	374+
22	10, 15, 15	Lymphocytopenia	No	PR	119	146	291+
23	15	Thrombocytopenia, anemia	Yes	PD	NA	26	85
24	10, 15, 10	Lymphocytopenia, anemia, myelodysplasia	Yes	PR	94	119	161
25	10, 15	None	No	CR	43+	110	143+
26	15	None	No	PD	NA	54	115+
27	10, 10	Thrombocytopenia	No	PR	40+	66	68+
28	10, 15	Lymphocytopenia	No	SD	NA	38	40+
29	10, 15 × 2	None	No	SD	NA	110	110+
30	10	Pneumonitis/pulmonary infiltrates	No	PD	NA	29	29+
31	15 × 3	None	No	SD	NA	112+	112+
32	15 × 3	None	No	CR	129	173	173+
33	10 × 3	Thrombocytopenia	No	PR	149	175	175+
34	10, 15 × 2	None	No	SD	NA	152	152+
		Anemia, lymphocytopenia
		Neutropenia
35	10	Neutropenia	Yes	SD	155
36	15	None	No	SD	NA	147	147+
37	10, 15 × 4	None	No	SD	NA	207	207+
38	10 × 2, 15 × 2	None	No	SD	NA	195	195+
39	10, 15	None	No	SD	NA	91	91+
40	10	Anemia, lymphocytopenia, neutropenia	No	SD	NA	31	31+
41	15 × 5	Lymphocytopenia	No	CR	720	788	788+
42	15	Lymphocytopenia	Yes	SD	NA	76	325+
43	10 × 2, 15	Myelodysplasia	No	CR	105	105	105+
44	10	None	No	PD	NA	28	28+
45	10, 15 × 4	None	Yes	PR	147	280	280+
46	10	None	No	PD	NA	32	32+

CR, complete remission; PD, progressive disease; PR, partial remission; SD, stable disease.