Table 1.

Patient-Reported and Clinical Data Collected at Each Visit

	Patient-Reported Data	Clinical Data from Medical Record
Symptoms	Pain intensity (Pain Numeric Rating Scale²⁶), quality, and pattern (investigator developed items)
	Dyspnea, fatigue, insomnia, anorexia, and overall symptom distress (Symptom Distress Scale⁴⁴)
	Depression (Personal Health Questionnaire-9⁴⁵)
	Anxiety (Hospital Anxiety and Depression Scale⁴⁶)
	Opioid-induced constipation (Constipation severity measure⁴⁷ and Patient Reported Outcomes version of the Common Terminology Criteria for Adverse Events – PRO-CTCAE v3^{73, 74})
Alcohol risk and drug allergies^a	Risk for hazardous alcohol use (Alcohol Use Disorders Identification Test⁴⁸)
		Drug allergies
Comorbidities ^a	History of peptic ulcer disease
Cancer therapy		Start and end dates of all regimens of chemotherapy, radiation, or targeted therapy
Lab values for visit date		Platelet count, serum creatinine, hemoglobin
Patient characteristics		Age, weight on visit date
Supportive care medications		Prescribed medications with dose and frequency (opioid and non-opioid pain medications, antidepressants, anxiolytics, hypnotics, psychostimulants, laxatives)
	Actual use of prescribed and over-the-counter supportive care medications

Data collected once at the beginning of the study and used at each visit.