Table 1. Regioselective ring opening of epoxide 1 with piperazine and piperidine derivatives afforded 5a-5e.

Entry	R1	X	Yield (%)
5a	CH3	N	92
5b	CH2CH3	N	87
5c	4-fluorobenzyl	N	89
5d	4-bromobenzyl	N	89
5e	piperidine	C	85