Table 2. Comparison within- and between the two training groups from baseline to 8-weeks follow-up.
Variable | Baseline | 8-wk follow-up | Mean change (95% CI) from baseline to 8-wk follow-up | p-value a (within group comparison) | p-value b (between group comparison) | Effect size c (within group) | Effect size c (between group) | |
---|---|---|---|---|---|---|---|---|
FAB scale d | RT | 22.2 ± 4.8 | 24.5 ± 5.4 | 2.4 (0.1; 4.6) | 0.04* | 0.143 | -0.46 | -0.59 |
BT | 24.5 ± 4.6 | 24.9 ± 5.3 | 0.3 (-0.8; 1.5) | 0.526 | -0.08 | |||
Forward pull e | RT | 2270.3 ± 375.1 | 2336.7 ± 274.0 | 66.4 (-138.2; 270.9) | 0.311 | 0.769 | -0.20 | -0.17 |
BT | 1807.4 ± 351.8 | 1836.6 ± 360.9 | 29.2 (-66.4; 124.9) | 0.239 | -0.08 | |||
Backward pull e | RT | 1882.3 ± 326.9 | 1782.1 ± 373.4 | -100.2 (-311.5; 111.0) | 0.286 | 0.332 | 0.29 | 0.42 |
BT | 1844.6 ± 411.4 | 1917.4 ± 362.7 | 72.8 (-261.4; 407.0) | 0.657 | -0.19 | |||
TUG (sec) | RT | 11.2 ± 3.2 | 9.5 ± 2.4 | -1.7 (-3.3; -0.1) | 0.033* | 0.139 | 0.60 | 0.69 |
BT | 9.2 ± 3.0 | 9.0 ± 1.8 | -0.2 (-1.3; 0.9) | 0.929 | 0.08 | |||
UPDRS total score | RT | 40.2 ± 12.5 | 38.5 ± 12.3 | -1.7 (-5.1; 1.8) | 0.347 | 0.272 | 0.14 | -0.38 |
BT | 37.7 ± 13.1 | 33.6 ± 12.3 | -4.1 (-7.3; -0.9) | 0.033* | 0.32 | |||
UPDRS motor score f | RT | 22.6 ± 8.8 | 22.2 ± 8.9 | -0.4 (-2.0; 1.2) | 0.568 | 0.911 | 0.04 | -0.51 |
BT | 20.3 ± 4.9 | 19.4 ± 6.7 | -0.9 (-3.0; 1.1) | 0.821 | 0.49 | |||
gait velocity (cm/sec) | RT | 104.3 ± 15.3 | 106.1 ± 15.0 | 1.8 (-5.2; 8.7) | 0.619 | 0.692 | -0.12 | -0.14 |
BT | 106.9 ± 18.3 | 106.8 ± 17.7 | -0.1 (-7.4; 7.4) | 0.776 | 0.01 | |||
stride length (cm) | RT | 80.6 ± 13.0 | 80.3 ± 11.7 | -0.4 (-4.5; 3.7) | 0.865 | 0.097 | 0.02 | 0.50 |
BT | 88.8 ± 15.7 | 91.5 ± 16.1 | 2.7 (-0.4; 5.9) | 0.131 | -0.17 | |||
double support time (msec) | RT | 156.6 ± 31.7 | 156.3 ± 35.5 | -0.3 (-8.4; 7.8) | 0.532 | 0.134 | 0.01 | 0.45 |
BT | 149.4 ± 24.9 | 155.0 ± 32.1 | 5.6 (-2.1; 13.3) | 0.11 | -0.19 | |||
stride time variability (%) | RT | 3.8 ± 1.0 | 3.7 ± 1.7 | -0.1 (-0.8; 0.6) | 0.334 | 0.413 | 0.07 | -0.53 |
BT | 3.9 ± 1.8 | 3.0 ± 0.8 | -0.9 (-2.0; 0.3) | 0.182 | 0.65 | |||
PCI (%) | RT | 6.6 ± 1.5 | 6.1 ± 1.8 | -0.5 (-1.1; 0.1) | 0.061 | 0.077 | 0.30 | 0.75 |
BT | 6.1 ± 1.4 | 6.9 ± 2.1 | 0.8 (-0.7; 2.3) | 0.286 | -0.45 | |||
Asymmetry Index | RT | 5.1 ± 4.1 | 6.0 ± 4.3 | 0.9 (-1.1; 0.1) | 0.82 | 0.959 | -0.21 | -0.22 |
BT | 4.9 ± 3.7 | 5.0 ± 5.3 | 0.1 (-1.6; 1.8) | 0.99 | -0.02 | |||
leg strength (MVC), LES (N) | RT | 393.8 ± 113.5 | 416.9 ± 91.0 | 23.0 (-15.5; 61.6) | 0.279 | 0.458 | -0.22 | -0.43 |
BT | 416.5 ± 129.6 | 408.8 ± 138.5 | -7.7 (-53.3; 37.8) | 0.925 | 0.06 | |||
leg strength (MVC), MAS (N) | RT | 401.8 ± 130.0 | 399.8 ± 85.7 | -2.0 (-48.2; 44.2) | 0.807 | 0.287 | 0.02 | 0.33 |
BT | 407.9 ± 134.4 | 426.2 ± 131.6 | 18.3 (-4.4; 41.1) | 0.133 | -0.14 | |||
peak RFD, LAS (N/msec) | RT | 1.5 ± 0.7 | 1.6 ± 0.8 | 0.1 (-0.4; 0.4) | 0.753 | 0.223 | -0.13 | 0.50 |
BT | 1.6 ± 1.0 | 1.8 ± 0.9 | 0.3 (0.0; 0.5) | 0.028** | -0.21 | |||
peak RFD, MAS (N/msec) | RT | 1.5 ± 1.0 | 1.5 ± 0.7 | 0.0 (-0.6; 0.5) | 0.972 | 0.503 | 0.00 | 0.40 |
BT | 1.4 ± 0.7 | 1.7 ± 0.9 | 0.3 (-0.2; 0.8) | 0.308 | -0.37 | |||
RFD, LAS (N/msec) | RT | 0.8 ± 0.6 | 0.9 ± 0.6 | 0.1 (-0.2; 0.5) | 0.249 | 0.627 | -0.17 | 0.31 |
BT | 0.7 ± 0.5 | 1.0 ± 0.6 | 0.3 (0.0; 0.5) | 0.056 | -0.54 | |||
RFD, MAS (N/msec) | RT | 0.8 ± 0.7 | 0.9 ± 0.6 | 0.1 (-0.3; 0.5) | 0.600 | 0.939 | -0.15 | -0.14 |
BT | 0.9 ± 0.7 | 0.9 ± 0.7 | 0.0 (-0.4; 0.4) | 0.507 | 0.00 |
FAB, Fullerton Advanced Balance; TUG, Timed-Up-and-Go-Test; LAS, less affected side; MAS, more affected side; MVC, maximal voluntary contraction; PCI, Phase Coordination Index; RFD, rate of force development (0-100ms); UPDRS, Unified Parkinson’s Disease Rating Scale
a p-value of Wilcoxon test
b p-value of independent samples Mann-Whitney-U-Test
c Cohen’s d was calculated as effect size
d blinded video rating
e values represent the area under the curve of the normalized vector length from 0–3 sec after the surface perturbation
f blinded video rating, without item 22 (rigidity)
RT, resistance training (n = 17); BT, balance training (n = 15)
*significant different (p<0.05)
**after Bonferroni-adjustment not significant.