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. 2015 Oct 26;10(10):e0140584. doi: 10.1371/journal.pone.0140584

Table 2. Comparison within- and between the two training groups from baseline to 8-weeks follow-up.

Variable Baseline 8-wk follow-up Mean change (95% CI) from baseline to 8-wk follow-up p-value a (within group comparison) p-value b (between group comparison) Effect size c (within group) Effect size c (between group)
FAB scale d RT 22.2 ± 4.8 24.5 ± 5.4 2.4 (0.1; 4.6) 0.04* 0.143 -0.46 -0.59
BT 24.5 ± 4.6 24.9 ± 5.3 0.3 (-0.8; 1.5) 0.526 -0.08
Forward pull e RT 2270.3 ± 375.1 2336.7 ± 274.0 66.4 (-138.2; 270.9) 0.311 0.769 -0.20 -0.17
BT 1807.4 ± 351.8 1836.6 ± 360.9 29.2 (-66.4; 124.9) 0.239 -0.08
Backward pull e RT 1882.3 ± 326.9 1782.1 ± 373.4 -100.2 (-311.5; 111.0) 0.286 0.332 0.29 0.42
BT 1844.6 ± 411.4 1917.4 ± 362.7 72.8 (-261.4; 407.0) 0.657 -0.19
TUG (sec) RT 11.2 ± 3.2 9.5 ± 2.4 -1.7 (-3.3; -0.1) 0.033* 0.139 0.60 0.69
BT 9.2 ± 3.0 9.0 ± 1.8 -0.2 (-1.3; 0.9) 0.929 0.08
UPDRS total score RT 40.2 ± 12.5 38.5 ± 12.3 -1.7 (-5.1; 1.8) 0.347 0.272 0.14 -0.38
BT 37.7 ± 13.1 33.6 ± 12.3 -4.1 (-7.3; -0.9) 0.033* 0.32
UPDRS motor score f RT 22.6 ± 8.8 22.2 ± 8.9 -0.4 (-2.0; 1.2) 0.568 0.911 0.04 -0.51
BT 20.3 ± 4.9 19.4 ± 6.7 -0.9 (-3.0; 1.1) 0.821 0.49
gait velocity (cm/sec) RT 104.3 ± 15.3 106.1 ± 15.0 1.8 (-5.2; 8.7) 0.619 0.692 -0.12 -0.14
BT 106.9 ± 18.3 106.8 ± 17.7 -0.1 (-7.4; 7.4) 0.776 0.01
stride length (cm) RT 80.6 ± 13.0 80.3 ± 11.7 -0.4 (-4.5; 3.7) 0.865 0.097 0.02 0.50
BT 88.8 ± 15.7 91.5 ± 16.1 2.7 (-0.4; 5.9) 0.131 -0.17
double support time (msec) RT 156.6 ± 31.7 156.3 ± 35.5 -0.3 (-8.4; 7.8) 0.532 0.134 0.01 0.45
BT 149.4 ± 24.9 155.0 ± 32.1 5.6 (-2.1; 13.3) 0.11 -0.19
stride time variability (%) RT 3.8 ± 1.0 3.7 ± 1.7 -0.1 (-0.8; 0.6) 0.334 0.413 0.07 -0.53
BT 3.9 ± 1.8 3.0 ± 0.8 -0.9 (-2.0; 0.3) 0.182 0.65
PCI (%) RT 6.6 ± 1.5 6.1 ± 1.8 -0.5 (-1.1; 0.1) 0.061 0.077 0.30 0.75
BT 6.1 ± 1.4 6.9 ± 2.1 0.8 (-0.7; 2.3) 0.286 -0.45
Asymmetry Index RT 5.1 ± 4.1 6.0 ± 4.3 0.9 (-1.1; 0.1) 0.82 0.959 -0.21 -0.22
BT 4.9 ± 3.7 5.0 ± 5.3 0.1 (-1.6; 1.8) 0.99 -0.02
leg strength (MVC), LES (N) RT 393.8 ± 113.5 416.9 ± 91.0 23.0 (-15.5; 61.6) 0.279 0.458 -0.22 -0.43
BT 416.5 ± 129.6 408.8 ± 138.5 -7.7 (-53.3; 37.8) 0.925 0.06
leg strength (MVC), MAS (N) RT 401.8 ± 130.0 399.8 ± 85.7 -2.0 (-48.2; 44.2) 0.807 0.287 0.02 0.33
BT 407.9 ± 134.4 426.2 ± 131.6 18.3 (-4.4; 41.1) 0.133 -0.14
peak RFD, LAS (N/msec) RT 1.5 ± 0.7 1.6 ± 0.8 0.1 (-0.4; 0.4) 0.753 0.223 -0.13 0.50
BT 1.6 ± 1.0 1.8 ± 0.9 0.3 (0.0; 0.5) 0.028** -0.21
peak RFD, MAS (N/msec) RT 1.5 ± 1.0 1.5 ± 0.7 0.0 (-0.6; 0.5) 0.972 0.503 0.00 0.40
BT 1.4 ± 0.7 1.7 ± 0.9 0.3 (-0.2; 0.8) 0.308 -0.37
RFD, LAS (N/msec) RT 0.8 ± 0.6 0.9 ± 0.6 0.1 (-0.2; 0.5) 0.249 0.627 -0.17 0.31
BT 0.7 ± 0.5 1.0 ± 0.6 0.3 (0.0; 0.5) 0.056 -0.54
RFD, MAS (N/msec) RT 0.8 ± 0.7 0.9 ± 0.6 0.1 (-0.3; 0.5) 0.600 0.939 -0.15 -0.14
BT 0.9 ± 0.7 0.9 ± 0.7 0.0 (-0.4; 0.4) 0.507 0.00

FAB, Fullerton Advanced Balance; TUG, Timed-Up-and-Go-Test; LAS, less affected side; MAS, more affected side; MVC, maximal voluntary contraction; PCI, Phase Coordination Index; RFD, rate of force development (0-100ms); UPDRS, Unified Parkinson’s Disease Rating Scale

a p-value of Wilcoxon test

b p-value of independent samples Mann-Whitney-U-Test

c Cohen’s d was calculated as effect size

d blinded video rating

e values represent the area under the curve of the normalized vector length from 0–3 sec after the surface perturbation

f blinded video rating, without item 22 (rigidity)

RT, resistance training (n = 17); BT, balance training (n = 15)

*significant different (p<0.05)

**after Bonferroni-adjustment not significant.