TABLE 2.
Virus passage | Substitution in rH5N3 genes |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
PB2 (aa 466) | PB1 (aa 633) | PA (aa 263) | HA (aa 387) | NP (aa 371) | NA |
M1 (aa 97) | NS1 (aa 193) | NEP |
||||
aa 82 | aa 293 | aa 329 | aa 36 | aa 52 | ||||||||
P0 | D | S | T | N | M | E | R | A | V | R | E | M |
P1 | D | S | T | N | T | G | R | A | V | R | E | M |
P2 | D | R | T | N | T | G | K | A | V | R | E | T |
P3 | D | R | T | D | T | G | K | T | V | R | E | T |
P4 | D | R | T | D | T | G | K | T | I | R | E | T |
P5 | N | R | K | D | T | G | K | T | I | Q | K | T |
P6 | N | R | K | D | T | G | K | T | I | Q | K | T |
aa, amino acid.