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. 2015 Aug 19;89(21):10860–10867. doi: 10.1128/JVI.01627-15

FIG 2.

FIG 2

Effects of TLR3, TLR7, MAVS, and TRIF deficiency on survival of CVA16-infected young mice. (A and B) Survival rates of 14-day-old WT (n = 9 and 5, respectively), TLR3−/− (n = 5 and 8, respectively), and TRIF−/− (n = 10 and 13, respectively) C57BL/6 mice infected with 1.5 × 104 PFU CVA16 (A) or 1.5 × 103 PFU CVA16 (B). (C and D) Survival rates of 14-day-old WT (n = 10 and 5, respectively) and MAVS−/− (n = 10 and 5, respectively) mice with a strain 129 background infected with 1.5 × 104 PFU CVA16 (C) or 1.5 × 103 PFU CVA16 (D). (E and F) Survival rates of 14-day-old WT (n = 9 and 5, respectively) and TLR7−/− (n = 10 and 6, respectively) C57BL/6 mice infected with 1.5 × 104 PFU CVA16 (E) or 1.5 × 103 PFU CVA16 (F).