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. 2015 Oct 20;21:235–240. doi: 10.12659/MSMBR.895555

Table 1.

Basal and stimulated NO production, iNOS content and phenotype CD markers in macrophages isolated from highly tumor-resistant C57BL/6N substrain and lowly tumor-resistant C57BL/6J substrain.

Substrain Survival after tumor induction, days Indices of NO generation system M1 marker, CD 80 M2 marker, CD206
C57BL/6N 19.5+0.5 Nitrite, μmol 80.6±5.6% 52.7±4.9%
Basal conditions Stimulated conditions
45.7±1.34 74.4±1.26
iNOS
Basal conditions Stimulated conditions
graphic file with name medscimonitbasicres-21-235-g003.jpg graphic file with name medscimonitbasicres-21-235-g004.jpg
C57BL/6J 15.6±0.6** Nitrite, μmol 4.0±0.3%** 58.8±4.7%
Basal conditions Stimulated conditions
29.6±1.43** 52.2±1.28**
iNOS
Basal conditions Stimulated conditions
graphic file with name medscimonitbasicres-21-235-g005.jpg graphic file with name medscimonitbasicres-21-235-g006.jpg

Immunograms of Western blot analysis are presented as inserts in the table; intensity of the black line reflects iNOS content in macrophages.

**

Significant difference between mouse substrains, p<0.01.