Skip to main content
. 2015 Oct 16;9:5671–5686. doi: 10.2147/DDDT.S90082

Figure 5.

Figure 5

Effect of TAT–DV1–BH3 on the expression of key molecules in the apoptosis.

Notes: MDA-MB-231 cells were treated with TAT–DV1–BH3 at 20 μM, 40 μM, or 80 μM for 72 hours. The expression level of the procaspase-8, -9, and -3 and active caspase-8 and -9 was examined using Western blotting assay. (A) Representative blots of procaspase-8, -9, and -3 and active caspase-8 and -9. (B) Bar graph showing the relative expression level of procaspase-8, -9, and -3 and active caspase-8 and -9. β-Actin acts as the internal control. Data are expressed as mean ± SD of three independent experiments. *P<0.05, **P<0.01, and ***P<0.001 by one-way ANOVA.

Abbreviations: BH3, Bcl-2 homology 3; TAT, transactivator of transcription; SD, standard deviation; ANOVA, analysis of variance.