Table 2.
Survival rates of three cell lines with different concentrations of three polypeptides (mean ± SD%)
| Polypeptides cell | TAT–DV1–BH3 (μM)
|
TAT–DV1 (μM)
|
DV1–BH3 (μM)
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| 20 | 40 | 80 | 20 | 40 | 80 | 20 | 40 | 80 | |
| MDA-MB-231 | 93.81±15.84 | 68.29±11.21 | 28.67±8.22* | 114.24±1.54 | 116.08±4.95 | 113.59±7.28 | 109.37±1.95 | 102.47±2.03 | 110.39±5.13 |
| MCF-7 | 93.88±11.97 | 73.70±10.38 | 36.97±4.22* | 108.60±2.22 | 98.38±2.16 | 112.41 ±1.97 | 103.76±1.99 | 99.55±2.53 | 100.89±2.53 |
| HEK-293 | 90.31±3.60 | 81.80±7.83 | 69.85±8.02 | 106.22±2.11 | 86.47±1.01 | 88.28±1.02 | 90.37±2.02 | 87.62±2.28 | 91.38±2.03 |
Note:
*
P<0.05.
Abbreviations: BH3, Bcl-2 homology 3; TAT, transactivator of transcription; SD, standard deviation.