Table 2.
Genotype and allele distributions of rs895819 in two groups
| Model | Genotype and allele | Cases | Controls | P-value | OR and 95% CI | Adjusted OR and 95% CIa |
|---|---|---|---|---|---|---|
| Codominant | AA | 199 (48.3%) | 205 (49.8%) | |||
| AG | 143 (34.7%) | 166 (40.2%) | 0.43 | 0.901 (0.670–1.214) | 0.871 (0.676–1.131) | |
| GG | 70 (17.0%) | 41 (9.9%) | 0.01 | 1.523 (1.124–2.231) | 1.541 (1.110–2.239) | |
| Dominant | AA | 199 (48.3%) | 205 (49.8%) | |||
| AG/GG | 213 (51.7%) | 207 (50.2%) | 0.676 | 1.231 (0.741–1.431) | 1.210 (0.754–1.524) | |
| Recessive | AA/AG | 342 (83.0%) | 371 (90.1%) | |||
| GG | 70 (17.0%) | 41 (9.9%) | 0.003 | 1.852 (1.226–2.798) | 1.855 (1.221–2.786) | |
| Overdominant | AG | 143 (34.7%) | 166 (40.2%) | |||
| AA/GG | 269 (65.3%) | 246 (59.8%) | 0.098 | 0.802 (0.622–1.221) | 0.810 (0.632–1.232) | |
| Allele | Allele A | 541 (65.7%) | 576 (69.9%) | |||
| Allele G | 283 (34.3%) | 248 (30.1%) | 0.065 | 1.213 (0.947–1.522) | 1.247 (0.913–1.652) |
Note:
a
OR and 95% CI were adjusted by sex, age, smoking, and drinking.
Abbreviations: OR, odds ratio; CI, confidence interval.