Table 6.
Simultaneous multiple regression analyses on neuropsychological measures (12th month) with neuroimaging predictors
| Neuropsychological measures at 12th month | Hippocampal atrophy
|
Basal ganglia lesions
|
PVCs
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| β | t | P-value | β | t | P-value | β | t | P-value | |
| MMSE | −0.3 | −2.2 | 0.03 | −0.2 | −1.9 | 0.07 | 0.0 | 0.1 | 0.94 |
| MMSE (orientation) | −0.2 | −1.6 | 0.1 | −0.2 | −1.3 | 0.2 | −0.0 | −0.3 | 0.8 |
| MMSE (attention) | −0.3 | −2.4 | 0.01 | −0.1 | −1.2 | 0.2 | −0.0 | −0.0 | 0.9 |
| MMSE (memory) | −0.3 | −2.4 | 0.02 | −0.1 | −0.5 | 0.6 | 0.1 | 0.8 | 0.4 |
| MMSE (language) | 0.1 | 1.1 | 0.3 | −0.3 | −2.4 | 0.02 | −0.1 | −0.8 | 0.4 |
| MMSE (praxis) | −0.1 | −1.0 | 0.3 | −0.1 | −0.6 | 0.6 | 0.1 | 0.7 | 0.5 |
| IST | −0.4 | −3.3 | 0.001 | −0.2 | −1.3 | 0.19 | −0.1 | −1.0 | 0.31 |
| IADL | 0.3 | 2.5 | 0.01 | 0.0 | 0.2 | 0.83 | −0.1 | −0.4 | 0.7 |
| Delayed recall | −0.4 | −3.8 | 0.00 | 0.0 | 0.3 | 0.7 | −0.1 | 0.4 | 0.7 |
| Recognition | −0.3 | −2.9 | 0.005 | −0.0 | −0.3 | 0.7 | −0.2 | −1.2 | 0.2 |
| TMT-B | 0.3 | 2.7 | 0.008 | 0.3 | 2.5 | 0.01 | 0.2 | 1.6 | 0.1 |
| TMT-A | 0.3 | 2.8 | 0.007 | 0.3 | 2.7 | 0.01 | 0.1 | 1.1 | 0.3 |
Note: For each predictor, the β, t statistic, and P-value are reported.
Abbreviations: β, beta weight; IADL, Instrumental Activities of Daily Living; IST, Isaacs Set Test; MMSE, mini–mental state examination; PVCs, periventricular changes; TMT-A, Trail Making Test, part A; TMT-B, Trail Making Test, part B.