Table 1.
Input parameters used in the economic model
| Parameter | Base case | Upper estimate | Lower estimate | Source |
|---|---|---|---|---|
| Costs | ||||
| Cataract surgery (weighted average day-case and in-patient) | £862.66 | £1121.46 | £603.86 | UK NHS reference costs 2011–12 (HRG code BZ02Z) [12] |
| Ophthalmology out-patient visit | £85.12 | £110.66 | £59.58 | UK NHS reference costs 2011–12 (service code 130) [12] |
| GP visits | £43.00 | £55.90 | £30.10 | PSSRU 2012 [13] |
| PCO (YAG laser posterior capsulotomy) | £506.42 | £658.35 | £354.49 | UK NHS reference costs 2011–12 (HRG code BZ04Z lens capsulotomy) [12] |
| Retinal detachment (vitrectomy) | £1615.65 | £2100.35 | £1130.96 | UK NHS reference costs 2011–12 (HRG code BZ21Z major vitreous retinal procedures) [12] |
| Endophthalmitis (vitreous tap; vitrectomy) | £760.11 | £988.14 | £532.08 | UK NHS reference costs 2011–12 (HRG codes BZ21Z and BZ23Z) [12] |
| CMO (fluorescein angiogram and OCT)a | £313.30 | £407.29 | £219.31 | Colquitt et al. [14] |
| Lost lens fragments (vitrectomy) | £451.69 | £587.20 | £316.18 | UK NHS reference costs 2011–12 (HRG code BZ23Z minor vitreous retinal procedures) [12] |
| Resources | ||||
| Out-patient visits surgery | 6.94 | 7.98 | 5.90 | Sach et al. [4] |
| Out-patient visits no surgery | 2.81 | Sach et al. [4] | ||
| GP visits surgery | 4.40 | 5.21 | 3.59 | Sach et al. [4] |
| GP visits no surgery | 4.00 | Sach et al. [4] | ||
| Incidence of complications | ||||
| PCO Year 1 | 3.49% | 5.24% | 1.75% | ECCERT [15] |
| PCO Year 2 | 9.49% | 14.24% | 4.75% | ECCERT [15] |
| PCO Year 3 | 5.06% | 7.59% | 2.53% | ECCERT [15] |
| Retinal detachment Year 1 | 0.26% | 0.39% | 0.13% | Erie et al. [16] |
| Retinal detachment year 2+ | 0.14% | 0.21% | 0.07% | Erie et al. [16] |
| Endophthalmitis | 0.10% | 0.15% | 0.05% | UK National Cataract Survey [17] |
| CMO | 1.62% | 2.43% | 0.81% | UK Cataract National Dataset [18] |
| Lost lens fragments | 0.45% | 0.68% | 0.23% | UK Cataract National Dataset [18] |
| HRQoL utilities | ||||
| HRQoL no surgery | 0.70 | Hiratsuka et al. [19] | ||
| HRQoL gain for surgical group | 0.08 | 0.14 | 0.017 | Hiratsuka et al. [19] |
| Reduction in utility for non-second-eye surgery group, per year | 0.002 | 0.004 | 0.0001 | ECCERT [15] |
| Other parameters | ||||
| Discount rate, benefits/costs | 3.50% | 6.00% | 1.5% | UK NICE reference case [6] |
CMO, cystoid macular oedema; PCO, posterior capsule opacification; VA, visual acuity; OCT, optical coherence tomography; HRQoL, health-related quality of life; GP, general practitioner; NICE, National Institute of Health and Care Excellence.
aCosts for fluorescein angiogram and OCT inflated to current prices.