Characterization of cell wall-associated proteins from C. neoformans cap 67. A. Secretory potential classified by the Fungal Secretome Database (FSD): SP (presence of signal peptide as identified by SignaIP 3.0); SP3 (signal peptide predicted by SigPred, SigCleave or RPSP); SL (subcellular localization predicted by PSort II and/or Target 1.1b); NS (nonclassical secretion, predicted by SecretomeP 1.0f), and not classified (described as not secretory). B. Percentage of fungal orthologs previously reported in the cell wall (CW), extracellular vesicles (vesicle), both locations (CW+vesicle), or in neither of these compartments (ND).