Figure 3.

Impact of starting microbiota and route of antibiotic administration on resulting changes in bacterial composition. The experiment represented in Figure 2 (mouse cohort 1) was repeated with different cohorts of wild-type C57BL/6 Jackson mice. Mice from cohort 2 were subdivided into 2 additional treatment groups, with the first group receiving antibiotics dissolved in water (A, E), and the other receiving antibiotics by daily oral gavage (B, F). Each stacked bar represents a mean of 3 mice per time point per treatment group (exception: F at day 22, where n = 2). Abbreviation: OTUs, operational taxonomic units.