Table 1.
Median Oral Human Papillomavirus Type 16 (HPV16) Load Across Study Characteristics Among the 88 Individuals With Oral HPV16 Infection in the Persistent Oral Papillomavirus Study
| Characteristics of Participants | Subjects, No. | Copies Per 100 000 Cells, No., Median | P for Higher HPV Loada |
|---|---|---|---|
| Type of infection | .03 | ||
| Incident | 35 | 3.1 | |
| Prevalent | 53 | 76.6 | |
| Age, yb | .02 | ||
| ≤45 | 31 | 8.6 | |
| 45–54 | 35 | 74.1 | |
| ≥55 | 22 | 101.0 | |
| Current cigarette smoker | .21 | ||
| No | 37 | 37.3 | |
| Yes | 51 | 65.2 | |
| Sex | .54 | ||
| Male (MACS) | 40 | 66.5 | |
| Female (WIHS) | 48 | 34.8 | |
| Ever had a tonsillectomy | .35 | ||
| No | 62 | 32.3 | |
| Yes | 21 | 48.8 | |
| Not sure | 5 | 28571.4 | |
| Oral sex partners in past 6 months, no. | .56 | ||
| 0 | 57 | 48.4 | |
| 1 | 14 | 15.0 | |
| ≥2 | 17 | 88.9 | |
| HIV status | .11 | ||
| Negative | 22 | 17.0 | |
| Positive | 66 | 57.4 | |
| HIV status, CD4+ T-cell count | .22 | ||
| Negative | 22 | 17.0 | |
| Positive, >500 cells/µL | 31 | 73.8 | |
| Positive, 200–499 cells/µL | 24 | 42.8 | |
| Positive, ≤ 200 cells/µL | 11 | 547.3 |
Abbreviations: HIV, human immunodeficiency virus; MACS, Multicenter AIDS Cohort Study; WIHS, Women's Interagency HIV Study.
a Calculated using the Mann–Whitney test for medians. Variables were considered as continuous, when possible (ie, age and number of oral sex partners).
b With each 10-year increase in age, the HPV16 load significantly increased by 10.6 HPV16 copies per 100 000 cells.