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Adverse events that occurred in >1% of patients with major depressive disorder at any time during 8 weeks of treatment with duloxetine or paroxetine
| paroxetine (n=146) % (n) |
duloxetine (n=150) % (n) |
|
|---|---|---|
| nausea | 16.4% (24) | 15.3% (23) |
| dry mouth | 9.6% (14) | 15.3% (23) |
| constipation | 8.2% (12) | 10.0% (15) |
| loss of appetite | 6.8% (10) | 8.0% (12) |
| dizziness | 6.8% (10) | 8.7% (13) |
| diarrhea | 6.2% (9) | 3.3% (5) |
| drowsiness | 4.1% (6) | 5.3% (8) |
| fatigue | 4.8% (7) | 3.3% (5) |
