TABLE 3.
Antibiotic resistance genes of Weissella species as revealed by in silico screening of the annotated genome sequences.
| Strains | Antibiotic resistance determinants detected by analysis in silico of genome sequences (locus_tag) | |||||
|---|---|---|---|---|---|---|
| Daunorubicin | Fosfomycin | Methicillin | Glycopeptide | Sulfonamide | Tetracycline | |
| W. ceti WS08 | – | 1 FosB (WS08_1256) | – | – | Sul (WS08_0966) | – |
| W. ceti WS74 | – | 1 FosB (WS74_1327) | – | – | Sul (WS74_1032) | – |
| W. ceti WS105 | – | 1 FosB (WS105_1321) | – | – | Sul (WS105_1028) | Tet (WS105_0392) |
| W. ceti NC36 | – | 1 MDT-FosB (WCNC_RS02205) | 2 MRP (WCNC_02142, WCNC_02627) | – | – | – |
| W. cibaria KACC 11862 | – | 1 MDT-FosB (ESE_RS0106205) | 3 MRP (ESE_RS0109255, ESE_RS0102540, ESE_RS0105180) | VanZ (ESE_RS0111030) | – | – |
| W. confusa LBAE C39-2 | – | 1 MDT-FosB (WEISSC39_RS10580) | 1 MRP (WEISSC39_RS07020) | VanZ (WEISSC39_RS04975) | – | – |
| W. halotolerans DSM 20190 | 1 DrrC (G414_RS0101040) | 1 MDT-FosB (G414_RS0105405) | 1 MRP (G414_RS0103120) | – | – | – |
| W. hellenica Wikim14 | 1 DrrC (TY24_RS06500) | 1 MDT-FosB (TY24_RS09455) | 2 MRP (TY24_RS04745, TY24_RS00485) | – | – | – |
| W. koreensis KACC 15510 | – | – | 2 MRP (WKK_01735, WKK_02350) | – | – | – |
| W. koreensis KCTC 3621 | – | 1 MDT-FosB (JC2156_RS02465) | 2 MRP (JC2156_RS06850, JC2156_07490) | – | – | – |
| W. oryzae SG25 | 1 DrrC (WOSG25_RS07165) | 1 MDT-FosB (WOSG25_RS02065) | 2 MRP (WOSG25_091020, WOSG25_RS07655) | – | – | – |
| W. paramesenteroides ATCC 33313 | – | 1 MDT-FosB (HMPREF0877_RS05895) | 2 MRP (HMPREF0877_RS07670, HMPREF0877_RS03440) | VanZ (HMPREF0877_1234) | – | – |
| W. thailandensis fsh4-2 | – | – | 1 MRP (WT2_00144) | – | – | Tet (WT2_00189) |
| Weissella sp. | ND | ND | ND | ND | ND | sul1, sul2 genes* |
DrrC, daunorubicin resistance protein; FosB, fosfomycin resistance protein; MDT-FosB, multidrug transporter involved in fosfomycin resistance; MRP, methicillin resistance protein; Sul, sulfonamide resistance protein; Tet, tetracycline resistance protein; VanZ, glycopeptide resistance protein. *Byrne-Bailey et al. (2009).