Table 1.
Study | Pathology | Gestation age in which miRNAs were detected (weeks) | Tissue used | ||
---|---|---|---|---|---|
Serum | Plasma | Placenta | |||
[28] [83] [44] |
PE | <20 26–40 <20 |
miR-210 ↑ miR-144 ↓ (severe and mild PE) miR-29a ↑ (mild PE) |
miR-210 ↑ (severe and mild PE) miR-210 ↑ |
|
[33, 51] | Perinatal | miR-16 ↑ (severe PE) | |||
[55] | 26 | miR-125b-1-3p ↑ | |||
[31, 39] | 39-40 | miR-155 ↑ (severe PE) | |||
[47] | 36 | miR-328 ↓ | |||
[32] | 5–12 13–25 26–40 |
miR-378a-5p ↓ | |||
[38] | Perinatal | miR-29b ↑ (severe late onset PE) | |||
[64] | Perinatal | miR-21 ↑ (early onset PE with IUGR) | |||
| |||||
[33] | IUGR | Perinatal | miR-16 ↑ miR-21 ↑ |
||
[69] | Perinatal | miR-424 ↑ | |||
| |||||
[72] | Gestational diabetes | Second trimester | miR-29a ↓ miR-222 ↓ miR-132 ↓ |
↓ indicates decrease in miRNA expression.
↑ indicates increase in miRNA expression.