Table 3.

Mean choroidal thickness in untreated fellow eyes of pretreated and treatment-naive patients prior to and after a loading dose of three 2 mg aflibercept injections at 4 weeks interval

Retinal area	Fellow eye—pretreated choroidal thickness (n=31)				Fellow eye—treatment-naive choroidal thickness (n=17)
	Before	After	Change	p Value	Before	After	Change	p Value
2500NCT	131.5±49.2	130.0±49.8	1.5±4.6	0.082	123.3±63.7	117.5±62.7	5.8±7.6	0.007
300NCT	195.5±47	193.7±48.0	1.7±4.7	0.051	216.6±81.8	209.3±83.7	7.3±9.2	0.002
SFCT	198.4±45.8	198.7±45.7	−0.3±3.9	0.645	222.5±80.2	218.5±82.7	4.0±11.9	0.067
300TCT	197.7±43.7	196.5±45.1	1.2±4.3	0.126	224.6±81.0	219.6±81.6	5.1±10.1	0.006
2500TCT	200.5±42.3	200.0±42.3	0.5±3.2	0.404	222.0±73.6	219.3±74.4	2.7±2.6	0.002

2500NCT=choroidal thickness 2500 µm nasal from the central fovea, 300NCT=choroidal thickness 300 µm nasal from the central fovea, SFCT=subfoveal choroidal thickness, 300TCT=choroidal thickness 300 µm temporal from the central fovea, 2500TCT=choroidal thickness 2500 µm temporal from the central fovea.

Data presented as mean±SD.