Figure 8. Homing GRN subcircuit shows striking resemblance to Drosophila RDGN.
(A) The perturbation analysis was mapped as a Biotapestry network model. (B) A retinal gene network subcircuit extracted from Drosophila (Kumar, 2009) shows a very similar circuit with few regulatory linkage changes in comparison.
Figure 8—figure supplement 1. The RDGN subcircuit is conserved throughout evolution.
Similar putative GRN models were deduced based on publications in systems also known to utilize RDGN components and assembled in Biotapestry: (A) Demosponge canal systems, (B) vertebrate skeletal myogenesis, and (C) the mouse otic placode.