Table 2.

Number of adverse events of MTX per treatment modality in 13 patients.

Event type	Low [≤12.5mg]		High [15-25mg]		Total:
	Oral	Injection	Oral	Injection
Increased ALT/AST > x 2	1		1	2	4
Nausea ± vomiting	3		1	2	6
Fatigue			1		1
Low-grade fever				1	1
Headache	1			1	2
General malaise			1		1
Rash		1			1
Joint pain	1				1
Total events:	6	1	4	6	17

MTX, methotrexate; ALT, alanine aminotransferase; AST; aspartate aminotransferase.