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In situ hybridization analysis of p21WAF1/CIP1 and c-myc mRNA in untreated and tachyplesin-treated SMMC-7721 cells ( × 536). The level of p21WAF1/CIP1 mRNA was low in SMMC-7721 cells (A) but high in the tachyplesin-treated cells (B). High level of c-myc mRNA was observed in SMMC-7721 cells (C) while the level of c-myc mRNA in the tachyplesin-treated cells down-regulated (D).
