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. 2015 Oct 27;6:307. doi: 10.3389/fphys.2015.00307

Table 1.

Summary of the most common human root malformations as against potentially affected processes of root development.

Root malformation Processes of root formation
Hertwig's epithelial root sheath Dentinogenesis Formation of furcation
Formation (crown-root transition) Apical proliferation (root elongation) Induction of odontoblast differentiation Disintegration, cementogenesis Epithelial bridge formation Interradicular dentinogenesis, cementogenesis
Short roots due to
   direct trauma Unaffected Disrupted Disrupted Continues Disrupted n.a.a n.a.a
   radiotherapy Unaffected Disrupted Disrupted Continues Continues Delayed Unaffected (?)
   chemotherapy Unaffected Disrupted Disrupted Continues Continues Delayed (?) Unaffected (?)
Root dilaceration Delayed (?) In wrong direction Unaffected Unaffected Unaffected Unaffected (?) Unaffected (?)
Taurodontism Unaffected Unaffected Unaffected Unaffected Unaffected Delayed Unaffected
Short root anomaly Unaffected Impaired Unaffected Unaffected Unaffected n.a.a n.a.a
Root malformation with CMD Unaffected Impaired Unaffected Unaffected Mechanically impaired Disturbed db: disrupted
cc: excessive
Double teeth Unaffected Unaffected Unaffected Unaffected Unaffected n.a.a n.a.a
Regional odontodysplasia Unaffected Impaired Unaffected (?) Unaffected Impaired Impaired Impaired (?)
Hypophosphatasia Unaffected Unaffected Unaffected Disd: unaffected (?) ace: impaired ccf: unaffected (?) Impaired (?) Unaffected Impaired (?)
Dentin dysplasia type I Unaffected Impaired Unaffected Unaffected Mechanically Impaired Impaired (?) db: mechanically impaired
a

not applicable, because malformation largely occurs in single rooted teeth;

b

d, dentinogenesis;

c

c, cementogenesis;

d

dis, disintegration;

e

ac, acellular cementum formation;

f

cc, cellular cementum formation.