Figure 1.

Conformations of Importin-β. (A) Structure of Importin-β, shown in cartoon representation with α-helices represented by cylinders, colored by HEAT repeats from the N-terminus (blue) to the C-terminus (red). (B) Conformational variety of crystal structures of Importin-β (PDB IDs are given in the legend). The centers of mass of the HEAT repeats are shown. Importin-β from different organisms (yImpβ: yeast; mImpβ: mouse; hImpβ: human). (C) Importin-β bound to the sIBB domain (magenta). To see this figure in color, go online.