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Noncompartmental parameter estimates
| Parameter, mean (CV) | Pharmacokinetic population (N = 145) |
|---|---|
| Clearance/F (L/h) | 464 (640) |
| Volume of distribution/F (L) | 2700 (274) |
| Absorption lag time (h) | 0.149 |
| AUC (ng h/mL) | 4.31 (64) |
| C max (ng/mL) | 0.573 (37) |
AUC area under the curve, C max maximum plasma concentration, CV coefficient of variation, F absolute bioavailability
