Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Nov;146(5):387–398. doi: 10.1085/jgp.201511475

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Santa Cruz et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 2. — Macroscopic properties: voltage gating of Cx40 mutant gap junctions. (Left) Gap junction currents (I_j) elicited by a bipolar pulse protocol from HeLa cells transfected with Cx40 mutants: A96S (A), G38D (B), and M163V (C). (Right) Summary plots of normalized g_j versus V_j. The continuous black lines represent the best fit of the data to the Boltzmann equation: (A) A96S (V_j,o = 49 mV, g_j,min = 0.20, and z = 2.1; n = 5); (B) G38D (V_j,o = 52 mV, g_j,min = 0.20, and z = 2.1; n = 7); (C) M163V (V_j,o = 48 mV, g_j,min = 0.22, and z = 3.1; n = 10). The dashed gray line corresponds to the Boltzmann fit of Cx40 data (V_j,o = 48 mV, g_j,min = 0.24, and z = 3.9; n = 6). Error bars represent means ± SEM.