Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Nov;146(5):343–356. doi: 10.1085/jgp.201511456

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Cherny et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 10. — Replacement of Trp²⁷⁸ in the coccolithophore EhH_V1 with Ala, Ser, or Phe hastens channel opening to the same extent. The activation time constant, τ_act, was determined by fitting the turn-on of current with a single rising exponential. The mean ratio of WT/W278X within the range of 10–60 mV was 3.5 (W278A), 5.7 (W278F), and 6.3 (W278S). Numbers of cells are: WT, three to six; W278A, three to four; W278F; two to four; W278S, two to three. Single mutants were expressed in HEK-293 or COS-7 cells, and measurements were performed in whole-cell configuration at symmetrical pH 7. Error bars represent mean ± SEM.