Table 6.
Variable | ISS < 15 ( n = 261) | ISS 15-24 (n = 96) | ISS ≥ 25 (n = 86) | P-value |
---|---|---|---|---|
5 pM TF/ 4 uM PS (PPP reagent) Lagtime (min) |
2.79 (2.38, 3.33) | 2.67 (2.33, 3.11) | 2.67 (2.20, 3.36) | <0.0001 |
Peak Height (nM) | 342.6 (293.2, 396.8) | 347.4 (290.2, 409.9) | 319.4 (267.6, 376.2) | <0.0001 |
ttPeak (min)# | 4.94 (4.33, 5.78) | 4.56 (4.06, 5.14) | 4.52 (3.92, 5.30) | <0.0001 |
1pM TF (PRP reagent) Lagtime (min) |
8.67 (7.11, 11.00) | 7.86 (6.67, 10.22) | 8.22 (6.64, 10.21) | <0.0001 |
Peak Height (nM) | 46.9 (33.2, 68.1) | 49.8 (34.0, 73.4) | 52.4 (35.9, 77.5) | 0.0071 |
ttPeak (min)# | 17.89 (15.33, 21.00) | 16.70 (14.05, 19.36) | 15.97 (13.56, 18.84) | <0.0001 |
Total Procoagulant MPs (per uL plasma) | 405.6 (211.5, 786.9) | 424.3 (237.9, 770.7) | 372.7 (197.8, 758.3) | 0.370 |
CD42 +, Procoagulant MPs (per uL plasma)* | 20.6 (11.1, 42.1) | 18.5 (9.9, 36.1) | 19.0 (9.1, 42.9) | 0.0520 |
ttPeak – Time to peak
CD42+, Procoagulant MPs – Platelet derived, procoagulant microparticles