Table 1. Pre- and Post-Transfusion Values for Cerebral Hemodynamics.
Variable | Total Median (IQR) n |
P-value (Posttfx-Pretfx) |
RBC (maximum) ≤ 21 days old Median (IQR) n |
P-value (Posttfx-Pretfx) |
RBC (maximum) > 21 days old Median (IQR) n |
P-value (Posttfx-Pretfx) |
P-value for difference in RBC≤21 vs. difference in RBC>21 groups |
|||
---|---|---|---|---|---|---|---|---|---|---|
Pretfx | Posttfx | Pretfx | Posttfx | Pretfx | Posttfx | |||||
Primary outcome: SjvO2 (n=59) | 73.0 (15.0) 63 | 76.0 (15.0) 63 | 0.02 | 74.0 (15.0) 27 | 76.0 (17.0) 26 | 0.07 | 71.5 (15.5) 36 | 76.0 (13.0) 37 | 0.11 | 0.54 |
Secondary outcome: PbtO2 (n=77) | 21.0 (16.7) 82 | 24.0 (18.1) 84 | 0.32 | 18.2 (16.6) 38 | 22.3 (18.8) 39 | 0.46 | 21.9 (15.7) 44 | 25.0 (19.4) 45 | 0.5 | 0.81 |
ICP (n=90) | 16.0 (8.0) 94 | 17.0 (9.0) 96 | 0.67 | 16.0 (9.0) 43 | 17.0 (9.0) 42 | 0.53 | 16.0 (9.0) 51 | 17.0 (9.0) 54 | 0.26 | 0.19 |
MAP (n=103) | 86.0 (21.0) 105 | 89.0 (16.0) 106 | 0.03 | 86.0 (17.0) 47 | 89.0 (15.0) 47 | 0.37 | 84.0 (23.0) 58 | 89.0 (17.0) 59 | 0.04 | 0.42 |
CPP (n=90) | 70.0 (21.0) 94 | 73.0 (19.0) 96 | 0.2 | 70.0 (21.5) 44 | 73.0 (21.0) 43 | 0.38 | 70.0 (20.0) 50 | 73.0 (16.0) 53 | 0.5 | 0.85 |
FV (n=71) | 90.0 (28.0) 71 | 88.0 (36.0) 71 | 0.22 | 90.0 (25.0) 37 | 88.0 (35.0) 37 | 0.76 | 90.5 (36.0) 34 | 88.0 (34.0) 34 | 0.14 | 0.46 |
FVOL (n=63) | 541.3 (380.3) 63 | 451.7 (316.7) 65 | <.01 | 545.0 (414.0) 33 | 462.2 (309.2) 34 | 0.15 | 529.9 (373.1) 30 | 380.0 (349.3) 31 | <.01 | 0.37 |
Hgb (n=110) | 9.0 (1.7) 110 | 10.2 (1.5) 110 | <.01 | 9.0 (1.5) 49 | 10.0 (1.4) 49 | <.01 | 8.7 (2.8) 61 | 10.2 (1.6) 61 | <.01 | 0.12 |
PaO2 (n=59) | 165.0 (84.0) 63 | 157.0 (71.0) 62 | 0.01 | 160.5 (81.5) 32 | 129.0 (82.0) 31 | 0.05 | 165.0 (104.0) 31 | 165.0 (63.0) 31 | 0.09 | 0.82 |
PaCO2 (n=60) | 36.5 (10.5) 64 | 38.0 (8.0) 63 | 0.62 | 35.0 (11.0) 33 | 36.0 (7.5) 32 | 0.95 | 38.0 (5.0) 31 | 38.0 (8.0) 31 | 0.34 | 0.51 |
Abbreviations: posttfx, post transfusion; pretfx, pre transfusion; RBC, red blood cell age