. Author manuscript; available in PMC: 2016 Nov 1.

Published in final edited form as: J Trauma Acute Care Surg. 2015 Nov;79(5):843–849. doi: 10.1097/TA.0000000000000834

Table 5. Cox Regression Analysis-average age of RBCs Adjusted for Pre-specified Covariates stratified by time.

		Unadjusted			Adjusted
Time interval (day after injury)	Number dead in interval	Hazard Ratio	95% Confidence Interval	p-value	Hazard Ratio	95% Confidence Interval	p-value

0-3	8	2.68	0.54-13.29	0.23	1.88^*	0.29-12.32	0.51
4-13	7	0.70	0.16-3.11	0.63	0.73^†	0.16-3.35	0.69
≥14	12	1.28	0.41-4.05	0.67	1.70^*	0.50-5.78	0.40

Adjusted for baseline variables EPO treatment group, the randomization transfusion threshold, injury severity score, and the IMPACT predicted probability of death.

^†

Adjusted for baseline variables EPO treatment group, injury severity score, and the IMPACT predicted probability of death (the randomization transfusion threshold was omitted from the adjustment of the model in time interval 4-13 days because all 7 dead were in the transfusion threshold <10g/dL group).