Table 4.

Multivariate Cox Regression Modeling: Adiposity Variable and Rectal Cancer Outcomes

	Disease-free survival				Overall survival
	Crude HR	Adjusted HR*	95% CI	p Value	Crude HR	Adjusted HR	95% CI	p Value
Overall (n = 96)
BMI
<30	1.00	1.00	Ref	0.36	1.00	1.00	Ref	0.31
≥30	1.51	1.52	0.63–3.67		1.77	1.77	0.59–5.32
V/S
<0.4	1.00	1.00	Ref	0.09	1.00	1.00	Ref	0.28
≥0.4	3.50	2.53	0.85–7.49		2.64	2.03	0.57–7.20
PNF, mm	1.03	1.01	0.97–1.06	0.52	1.06	1.04	0.99–1.09	0.16
Well-moderately differentiated tumors (n = 90)
BMI
<30	1.00	1.00	Ref	0.16	1.00	1.00	Ref	0.23
≥30	1.75	1.97	0.76–5.10		1.98	2.09	0.64–6.86
V/S
<0.4	1.00	1.00	Ref	0.03	1.00	1.00	Ref	0.17
≥0.4	5.45	4.99	1.15–21.63		3.14	2.89	0.64–13.10
PNF, mm	1.03	1.03	0.99–1.07	0.22	1.05	1.05	0.99–1.11	0.09

^*Adjusted for grade (poorly differentiated vs well differentiated/moderate) and pathologic response (none/partial vs complete).

BMI, body mass index; HR, hazard ratio; PNF, perinephric fat thickness; SFA, subcutaneous fat area; VFA, visceral fat area; V/S, visceral fat to subcutaneous fat ratio.