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. 2015 Oct 26;16:869. doi: 10.1186/s12864-015-2102-3

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© Steele et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Categorical analysis of changes in gene expression based on lung disease severity categorized by % predicted D_LCO (top) or % predicted FVC (bottom) for novel IIP candidate genes rhotekin 2 (RTKN2 - left), selectin E (SELE - middle), and peptidase inhibitor 15 (PI15 – right). Mild, moderate, and severe are defined as percent predicted D_LCO (mild ≥65 %, moderate <65 % and >35 %, and severe ≤35 %), or FVC (mild ≥75 %, moderate <75 % and >40 %, and severe ≤40 %). p values for severe vs mild groups are shown in Table 2