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. 2015 Oct 26;10:55. doi: 10.1186/s13024-015-0052-5

Table 1.

Half-lives of various tau species in pro-aggregant mice and anti-aggregant mice

Pro-aggregant mice
	half-life (t_1/2, day)	R²
Intracellular soluble	9.7	0.91
Extracellular soluble	17.3	0.7
P		0.06
intracellular soluble	9.7	0.91
intracellular soluble pS202/pT205	5.7	0.8
P		0.12
intracellular soluble	9.7	0.91
intracellular soluble pT231/pS235	5.2	0.88
P		<0.0001
intracellular soluble	9.7	0.91
intracellular insoluble	34.2	0.43
P		<0.0001
intracellular soluble	9.7	0.91
intracellular soluble pS396	9.8	0.51
P		0.52
Anti-aggregant mice
	half-life (t_1/2, day)	R²
Intracellular soluble	11.1	0.96
Extracellular soluble	10.9	0.91
P		0.44
	half-life (t_1/2, day)	R²
intracellular soluble	11.1	0.96
intracellular soluble pS202/pT205	7.5	0.89
P		0.022
	half-life (t_1/2, day)	R²
intracellular soluble	11.1	0.96
intracellular soluble pS396	7.6	0.64
P		0.24