Table 2. List of top 5 up- and down-regulated, novel candidate genes in Dentate Gyrus and Lateral Entorhinal Cortex after 7 days of AICAR administration (ACR7) and exercise (RUN7).
DENTATE GYRUS | LATERAL ENTORHINAL CORTEX | ||||||||
---|---|---|---|---|---|---|---|---|---|
GENE | FOLD | Z RATIO | GENE | FOLD | Z RATIO | ||||
ACR7 | RUN7 | ACR7 | RUN7 | ACR7 | RUN7 | ACR7 | RUN7 | ||
Wdr37 | 1.83 | 2.06 | 3.73 | 4.21 | Igsf1 | 3.21 | 2.29 | 9.34 | 6.72 |
Armc8 | 1.79 | 1.98 | 4.67 | 4.65 | Nr2f2 | 2.40 | 2.37 | 8.29 | 8.33 |
Phactr1 | 1.77 | 1.71 | 1.46 | 0.79 | Smpdl3b | 2.35 | 2.10 | 6.96 | 5.97 |
Zmpste24 | 1.76 | 1.70 | 3.92 | 3.08 | Tmie | 2.19 | 1.93 | 6.27 | 5.28 |
Pfkp | 1.67 | 2.23 | 2.65 | 3.03 | Gm4983 | 1.90 | 1.96 | 5.95 | 6.45 |
Ift122 | −1.56 | −1.71 | −2.04 | −2.53 | Scn1a | −2.19 | −1.79 | −5.89 | −5.02 |
Trmt1 | −1.59 | −1.57 | −2.44 | −2.23 | Cd6 | −2.35 | −1.92 | −6.35 | −4.97 |
Fam193b | −1.64 | −1.90 | −2.74 | −3.35 | R3 hdm | −2.70 | −1.61 | −7.89 | −4.40 |
Lrrc45 | −1.80 | −2.16 | −2.80 | −3.71 | Myl4 | −2.78 | −2.22 | −7.65 | −6.05 |
Erich5 | −2.95 | −4.22 | −7.20 | −7.82 | Tnnc1 | −3.35 | −2.39 | −8.91 | −6.42 |