Table 1. Association between serum miR-26a expression and clinicopathological variables of CCA patients.
| Clinicopathological features | No. | Relative miR-26a expression (mean ± SD) | P |
|---|---|---|---|
| Age at diagnosis (years) | |||
| ≤ 60 | 32 | 3.09 ± 2.27 | 0.654 |
| > 60 | 34 | 3.13 ± 2.32 | |
| Gender | |||
| Male | 38 | 3.04 ± 2.38 | 0.609 |
| Female | 28 | 3.20 ± 2.18 | |
| Clinical stage at diagnosis | |||
| I-II | 29 | 2.29 ± 1.44 | 0.005* |
| III-IV | 37 | 3.75 ± 2.61 | |
| Invasion depth | |||
| T1-T2 | 27 | 3.18 ± 2.36 | 0.776 |
| T3-T4 | 39 | 3.67 ± 2.60 | |
| Lymph vessel infiltration | |||
| Yes | 24 | 4.14 ± 2.17 | 0.007* |
| No | 42 | 2.71 ± 2.04 | |
| Distant metastasis | |||
| Yes | 10 | 4.50 ± 2.87 | 0.036* |
| No | 56 | 2.86 ± 2.10 | |
| Differentiation | |||
| Well | 39 | 2.54 ± 1.79 | 0.013* |
| Moderate/Poor | 27 | 3.94 ± 2.67 |
*
Significant relation of clinical factors with overall survival